Applegate, joked as she joined host Anthony Anderson on stage during the Monday, January 15, broadcast, saying.

Applegate, who has been battling multiple sclerosis for years, continued to bring the laughs as the crowd gave her a standing ovation.

"It's been an honor to play funny, flawed, complex characters like the women nominated in supporting actress in a comedy series.

Applegate continued, announcing ayo edebiri as the winner for her appearance on 'The Bear'.

Applegate, who is nominated for lead actress in a comedy for "Dead To Me", has kept a low profile since announcing her multiple sclerosis diagnosis in august 2021.

Applegate has been nominated for eight Emmys throughout her career.

She won in 2003 for outstanding guest actress in a comedy series while playing amy on 'Friend'.